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MultimediaMost patients with major depressive disorder will not achieve remission with initial treatment. Strategies to increase the likelihood of achieving remission include regularly measuring response, assessing adverse effects and adherence, addressing non-mood symptoms, and knowing when to switch or augment antidepressants. In this CME Health Spectrum activity, follow 2 patient cases that illustrate these topics. [top]

Advanced Topics in Major Depressive Disorder: Practical Strategies to Improve Remission

Advanced Topics in Major Depressive Disorder: Practical Strategies to Improve Remission

Rakesh Jain, MD, MPH

Complicated OCD: Issues of Comorbidity and Clinical Challenges

Presentation and Treatment of Complicated Obsessive-Compulsive Disorder

Charles F. Brady, PhD, ABPP

Depression: Addressing Partial Response After First-Line Antidepressant Treatment

Strategies for Achieving Full Remission When First-Line Antidepressants Are Not Enough

Andrew A. Nierenberg, MD

Schizophrenia: Using Long-Acting Injectable Antipsychotics to Improve Treatment Adherence

Addressing Barriers to Using Long-Acting Injectable Antipsychotics and Appropriately Monitoring Antipsychotic Adverse Effects

Christoph U. Correll, MD

Schizophrenia: When First-Line Treatment Fails

Addressing Nonresponse in Schizophrenia

John M. Kane, MD

Evidence for Using L-Methylfolate Combined With Antidepressants in MDD

Evidence for the Use of l-Methylfolate Combined With Antidepressants in MDD

Maurizio Fava, MD (Chair), et al

Managing Bipolar Disorder From Urgent Situations to Maintenance Therapy

A Clinician's View of the Data on Bipolar Disorder

Noel C. Gardner, MD

CME From JCPDescriptions of mixed states can be found in the writings of ancient Greek physicians, and the concept continues to be refined. In this CME activity, join experts as they review the current diagnostic criteria for depressive episodes with mixed features, the risk of developing bipolar disorder in patients with this diagnosis, and recent treatment guidelines. [top]

Diagnosing and Treating Patients With Mixed Features

Diagnosing and Treating Patients With Mixed Features

Rakesh Jain, MD, MPH (Chair), et al

JCP CME Activities

Mindfulness-Based Stress Reduction for Older Adults With Stress Disorders and Neurocognitive Difficulties: A Randomized Controlled Trial

Julie Loebach Wetherell, Tamara Hershey, Steven Hickman, Susan R. Tate, David Dixon, Emily S. Bower, and Eric J. Lenze

Florida Best Practice Psychotherapeutic Medication Guidelines for Adults With Major Depressive Disorder

Roger S. McIntyre, Trisha Suppes, Rajiv Tandon, and Michael Ostacher

Depression and Anxiety in the Postpartum Period and Risk of Bipolar Disorder: A Danish Nationwide Register-Based Cohort Study

Xiaoqin Liu, Esben Agerbo, Jiong Li, Samantha Meltzer-Brody, Veerle Bergink, and Trine Munk-Olsen

National Trends in Antidepressant, Benzodiazepine, and Other Sedative-Hypnotic Treatment of Older Adults in Psychiatric and Primary Care

Donovan T. Maust, Frederic C. Blow, Ilse R. Wiechers, Helen C. Kales, and Steven C. Marcus

Short-Term Naturalistic Treatment Outcomes in Cigarette Smokers With Substance Abuse and/or Mental Illness

Short-Term Naturalistic Treatment Outcomes in Cigarette Smokers With Substance Abuse and/or Mental Illness

Risa B. Gershon Grand, Sun Hwang, Juliette Han, Tony George, and Arthur L. Brody

CME From PCCResearch on behavioral activation (BA) teletherapy is limited. Learn about a brief BA teletherapy program for depression and anxiety in a study describing results among low-income, real-world primary care patients. [top]

PCC CME Activities

Efficacy of a Behavioral Activation Teletherapy Intervention to Treat Depression and Anxiety in Primary Care VitalSign6 Program

Joseph M. Trombello, Charles South, Audrey Cecil, Katherine E. Sánchez, Alma Christina Sánchez, Sara Levinson Eidelman, Taryn L. Mayes, Farra Kahalnik, Corey Tovian, Beth D. Kennard, and Madhukar H. Trivedi

Mental and Physical Health Conditions in US Combat Veterans: Results From the National Health and Resilience in Veterans Study

Melissa M. Thomas, Ilan Harpaz-Rotem, Jack Tsai, Steven M. Southwick, and Robert H. Pietrzak

Mood Versus Memory

Anna D. Burke, William J. Burke, Garrett H. Riggs, David A. Weidman, and Jacquelynn N. Copeland

Mixed Specifier for Bipolar Mania and Depression: Highlights of DSM-5 Changes and Implications for Diagnosis and Treatment in Primary Care

Jia Hu, Rodrigo Mansur, and Roger S. McIntyre