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CME From JCPWhen you see older patients, do you verify the appropriateness of their prescribed psychotropic drugs? Prescriptions of antidepressants, benzodiazepines, and sedative-hypnotics have increased in this population, even among patients with no mental health diagnosis. Read this journal CME article comparing trends in psychiatry versus primary care. [top]

Journal CME Activities

National Trends in Antidepressant, Benzodiazepine, and Other Sedative-Hypnotic Treatment of Older Adults in Psychiatric and Primary Care

Donovan T. Maust, Frederic C. Blow, Ilse R. Wiechers, Helen C. Kales, and Steven C. Marcus

Adverse Childhood Experiences and Risk for First-Episode Major Depression During the Menopause Transition

Cynthia Neill Epperson, Mary D. Sammel, Tracy L. Bale, Deborah R. Kim, Sarah Conlin, Stephanie Scalice, Katharine Freeman, and Ellen W. Freeman

Identifying Remission From Depression on 3 Self-Report Scales

Mark Zimmerman, Emily Walsh, Michael Friedman, Daniela A. Boerescu, and Naureen Attiullah

Antipsychotic Drug Interactions and Mortality Among Nursing Home Residents With Cognitive Impairment

Rosa Liperoti, Federica Sganga, Francesco Landi, Eva Topinkova, Michael D. Denkinger, Henriëtte G. van der Roest, Andrea D. Foebel, Harriet Finne-Soveri, Roberto Bernabei, and Graziano Onder

Adherence to Selective Serotonin and Serotonin-Norepinephrine Reuptake Inhibitor Prescriptions Affects Overall Medication Adherence in Older Persons: Evidence From the Italian Nationwide OsMed Health-DB Database

Alessandra Marengoni, Graziano Onder, Luca Degli Esposti, Pierluigi Russo, Diego Sangiorgi, Stefano Buda, Massimo Fini, Niccolò Marchionni, Stefano Bonassi, Federica Mammarella, Walter Marrocco, Giuseppe Pozzi, Katie Palmer, Alessandro Monaco, Sergio Pecorelli, Luca Pani, on behalf of the Geriatrics Steering Committee of the Italian Medicines Agency on behalf of the OsMed Health-DB Network

Medication Discrepancies at Outpatient Departments for Mood and Anxiety Disorders in the Netherlands: Risks and Clinical Relevance

Mirjam Simoons, Hans Mulder, Arne J. Risselada, Frederik W. Wilmink, Robert Schoevers, Henricus G. Ruhé, and Eric N. van Roon

Increasing Versus Maintaining the Dose of Olanzapine or Risperidone in Schizophrenia Patients Who Did Not Respond to a Modest Dosage: A Double-Blind Randomized Controlled Trial

Hitoshi Sakurai, Takefumi Suzuki, Robert R. Bies, Bruce G. Pollock, Masaru Mimura, Shitij Kapur, and Hiroyuki Uchida

The Perinatal Depression Treatment Cascade: Baby Steps Toward Improving Outcomes

Elizabeth Q. Cox, Nathaniel A. Sowa, Samantha E. Meltzer-Brody, and Bradley N. Gaynes

A Systematic Review of the Evidence for Medical Marijuana in Psychiatric Indications

Samuel T. Wilkinson, Rajiv Radhakrishnan, and Deepak Cyril D’Souza

Nonmedical Stimulant Use in College Students: Association With Attention-Deficit/Hyperactivity Disorder and Other Disorders

Timothy Wilens, Courtney Zulauf, MaryKate Martelon, Nicholas R. Morrison, Andrew Simon, Nicholas W. Carrellas, Amy Yule, and Rayce Anselmo

Nonmedical Prescription Opioid Use and DSM-5 Nonmedical Prescription Opioid Use Disorder in the United States

Tulshi D. Saha, Bradley T. Kerridge, Risë B. Goldstein, S. Patricia Chou, Haitao Zhang, Jeesun Jung, Roger P. Pickering, W. June Ruan, Sharon M. Smith, Boji Huang, Deborah S. Hasin, and Bridget F. Grant

Benzodiazepine Use and Risk of Mortality Among Patients With Schizophrenia: A Retrospective Longitudinal Study

Cynthia A. Fontanella, John V. Campo, Gary S. Phillips, Danielle L. Hiance-Steelesmith, Helen Anne Sweeney, Kwok Tam, Douglas Lehrer, Robert Klein, and Mark Hurst

Guideline Adherence for Mentally Ill Reproductive-Aged Women on Treatment With Valproic Acid: A Retrospective Chart Review

Dorothy Gotlib, Elizabeth Perelstein, Jacob Kurlander, Kara Zivin, Michelle Riba, and Maria Muzik

Late-Life Exacerbation of PTSD Symptoms in US Veterans: Results From the National Health and Resilience in Veterans Study

Natalie Mota, Jack Tsai, Paul D. Kirwin, Ilan Harpaz-Rotem, John H. Krystal, Steven M. Southwick, and Robert H. Pietrzak

Risk of Suicide Attempt and Suicide Death Following Completion of the Patient Health Questionnaire Depression Module in Community Practice

Gregory E. Simon, Karen J. Coleman, Rebecca C. Rossom, Arne Beck, Malia Oliver, Eric Johnson, Ursula Whiteside, Belinda Operskalski, Robert B. Penfold, Susan M. Shortreed, and Carolyn Rutter

Antidepressant Treatment and Risk of Dementia: A Population-Based, Retrospective Case-Control Study

Cynthia Wei-Sheng Lee, Cheng-Li Lin, Fung-Chang Sung, Ji-An Liang, and Chia-Hung Kao

Prevalence and Impact of Obsessive-Compulsive Symptoms in Depression: A STAR*D Report

Lee Baer, Madhukar H. Trivedi, Ilana Huz, A. John Rush, Stephen R. Wisniewski, and Maurizio Fava

Antipsychotic Treatment of Adults in the United States

Mark Olfson, Marissa King, and Michael Schoenbaum

Marijuana Use Is Associated With Worse Outcomes in Symptom Severity and Violent Behavior in Patients With Posttraumatic Stress Disorder

Samuel T. Wilkinson, Elina Stefanovics, Robert A. Rosenheck

Influence of Schizophrenia Diagnosis on Providers’ Practice Decisions

Greer Sullivan, Dinesh Mittal, Christina M. Reaves, Tiffany F. Haynes, Xiaotong Han, Snigdha Mukherjee, Scott Morris, Laura Marsh, and Patrick W. Corrigan

Childhood Maltreatment and Risk of Suicide Attempt: A Nationally Representative Study

Nicolas Hoertel, Silvia Franco, Melanie M. Wall, Maria A. Oquendo, Shuai Wang, Frédéric Limosin, and Carlos Blanco

Precursors of Bipolar Disorders: A Systematic Literature Review of Prospective Studies

Gianni L. Faedda, Ciro Marangoni, Giulia Serra, Paola Salvatore, Gabriele Sani, Gustavo H. Vázquez, Leonardo Tondo, Paolo Girardi, Ross J. Baldessarini, and Athanasios Koukopoulos

Posttraumatic Stress Disorder in the US Veteran Population: Results From the National Health and Resilience in Veterans Study

Blair E. Wisco, Brian P. Marx, Erika J. Wolf, Mark W. Miller, Steven M. Southwick, and Robert H. Pietrzak

Depression and Multimorbidity: A Cross-Sectional Study of 1,751,841 Patients in Primary Care

Daniel J. Smith, Helen Court, Gary McLean, Daniel Martin, Julie Langan Martin, Bruce Guthrie, Jane Gunn, and Stewart W. Mercer

Metabolic Syndrome in a French Cohort of Patients With Bipolar Disorder: Results From the FACE-BD Cohort

Ophélia Godin, Bruno Etain, Chantal Henry, Thierry Bougerol, Philippe Courtet, Leroux Mayliss, Christine Passerieux, Jean-Michel Azorin, Jean-Pierre Kahn, Sebastien Gard, Dominique Costagliola, and Marion Leboyer for the FondaMental Advanced Centers of Expertise in Bipolar Disorders (FACE-BD) Collaborators

Postdeployment Suicidal Ideations and Trajectories of Posttraumatic Stress Disorder in Danish Soldiers: A 3-Year Follow-Up of the USPER Study

Trine Madsen, Karen-Inge Karstoft, Mette Bertelsen, and Søren Bo Andersen

Demographic, Economic, and Clinical Correlates of Depression Treatment Response in an Underserved Primary Care Population

Dinesh Mittal, Lakshminarayana Chekuri, Liya Lu, and John C. Fortney

Prescription Drug Monitoring Program Inquiry in Psychiatric Assessment: Detection of High Rates of Opioid Prescribing to a Dual Diagnosis Population

Daniel T. Hackman, Marion S. Greene, Taya J. Fernandes, Ashley M. Brown, Eric R. Wright, and R. Andrew Chambers

Guidelines for Preventing Common Medical Complications of Catatonia: Case Report and Literature Review

Kimberly Clinebell, Pierre N. Azzam, Priya Gopalan, and Roger Haskett

Repetitive Transcranial Magnetic Stimulation for Treatment-Resistant Depression: A Systematic Review and Meta-Analysis

Bradley N. Gaynes, Stacey W. Lloyd, Linda Lux, Gerald Gartlehner, Richard A. Hansen, Shannon Brode, Daniel E. Jonas, Tammeka Swinson Evans, Meera Viswanathan, and Kathleen N. Lohr

Recognizing and Treating Excessive Daytime Sleepiness and Narcolepsy

Managing Excessive Daytime Sleepiness

Thomas Roth, PhD (Chair), and Russell P. Rosenberg, PhD

Using Mechanism of Action to Choose Medications for Treatment-Resistant Depression

Choosing Medications for Treatment-Resistant Depression Based on Mechanism of Action

Michael E. Thase, MD (Chair), and Thomas L. Schwartz, MD

Overcoming Challenges in the Diagnosis and Management of ADHD in African American Adults

Culturally Competent Strategies for Assessing and Treating ADHD in African American Adults

Anthony L. Rostain, MD (Chair), et al

Depression: Addressing Partial Response After First-Line Antidepressant Treatment

Depression: Addressing Partial Response After First-Line Antidepressant Treatment

Michael E. Thase, MD (Chair), et al

Update on Best Practices for Managing Bipolar Depression

Update on Best Practices for Managing Bipolar Depression

Gary S. Sachs, MD, and Terence A. Ketter, MD

CME From PCCThe symptoms of dementia and depression frequently overlap. What are the best steps to take to differentiate between dementia and depression? Follow along with this case report to learn more about the diagnosis and treatment of a 50-year-old woman with cognitive impairment, bipolar II disorder, and a family history of Alzheimer's disease. [top]

Companion CME Activities

Mood Versus Memory

Anna D. Burke, William J. Burke, Garrett H. Riggs, David A. Weidman, and Jacquelynn N. Copeland

Long-Acting Injectable Antipsychotics for Schizophrenia: Sociodemographic Characteristics and Treatment Adherence

James McCreath, Essie Larson, Purabi Bharatiya, Hisham A. Labanieh, Zvi Weiss, and Michael Lozovatsky

Cardiometabolic Assessment, Diagnosis, and Treatment of Chronic Medical Illnesses During an Inpatient Psychiatric Hospitalization: Colocated Medical Care Versus Treatment as Usual

Jason R. Tatreau, Suzanne Harris, Brian Sheitman, and Beat D. Steiner

Bright Light Therapy as Augmentation of Pharmacotherapy for Treatment of Depression: A Systematic Review and Meta-Analysis

Thomas M. Penders, Cornel N. Stanciu, Alexander M. Schoemann, Phillip T. Ninan, Richard Bloch, and Sy A. Saeed

At a Loss for Words

David A. Weidman, Anna D. Burke, Garret H. Riggs, Helle Brand, Jacquelynn N. Copeland, and William J. Burke

Student Evaluation of the Yellow Ribbon Suicide Prevention Program in Midwest Schools

Alexandra Flynn, Rosalee Zackula, Nicole M. Klaus, Liz McGinness, Susan Carr, and Matthew Macaluso

Managing Depression Among Homeless Mothers: Pilot Testing an Adapted Collaborative Care Intervention

Linda Weinreb, Carole C. Upshur, Debbian Fletcher-Blake, George Reed, and Christine Frisard

Movements and Memory

Anna D. Burke, Garret H. Riggs, David A. Weidman, Helle Brand, and William J. Burke

Sleep Duration and Insomnia Symptoms as Risk Factors for Suicidal Ideation in a Nationally Representative Sample

Subhajit Chakravorty, H.Y. Katy Siu, Linden Lalley-Chareczko, Gregory K. Brown, James C. Findley, Michael L. Perlis, and Michael A. Grandner

Association Between Specific Depression Symptoms and Glycemic Control Among Patients With Comorbid Type 2 Diabetes and Provisional Depression

Stephanie J. Czech, Susan M. Orsillo, Paul A. Pirraglia, Thomas M. English, and Alexa J. Connell

Reducing Adverse Polypharmacy in Patients With Borderline Personality Disorder: An Empirical Case Study

Alok Madan, John M. Oldham, Sylvia Gonzalez, and J. Christopher Fowler

Wernicke’s Encephalopathy: Increasing Clinician Awareness of This Serious, Enigmatic, Yet Treatable Disease

Alexandra Flynn, Matthew Macaluso, Inna D’Empaire, and Megan M. Troutman

Diagnosis and Management of Sleep Disorders in Posttraumatic Stress Disorder: A Review of the Literature

Shahla Mohsenin, MD, and Vahid Mohsenin, MD

Review of Evidence for Use of Antidepressants in Bipolar Depression

Shane J. McInerney, MB, MSc, MRCPsych, and Sidney H. Kennedy, MD, FRCPC

A Cross-Sectional Study of Major Repeaters: A Distinct Phenotype of Suicidal Behavior

Hilario Blasco-Fontecilla, MD, PhD; Isabelle Jaussent, PhD; Emilie Olié, MD, PhD; Severine Béziat, MSc; Sebastien Guillaume, MD, Paula Artieda-Urrutia, Enrique Baca-Garcia, Jose de Leon, and Philippe Courtet

Pharmacologic Treatment of Dimensional Anxious Depression: A Review

Dawn F. Ionescu, Mark J. Niciu, Erica M. Richards, and Carlos A. Zarate, Jr

Strategies to Improve Outcomes for Primary Care Patients With Major Depressive Disorder

Improving Outcomes for Primary Care Patients With Depression

Rakesh Jain, MD, MPH (Chair), et al

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