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  • Schizophrenia: Overview and Dopamine Dysfunction

    Anissa Abi-Dargham, MD

    Does dopamine dysfunction account for the negative and cognitive symptoms seen in schizophrenia? Get an overview of dopamine dysfunction and find out why this treatment target may be limited for patients with schizophrenia.

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  • Understanding the Sleep-Wake Cycle: Sleep, Insomnia, and the Orexin System

    Andrew D. Krystal, MD, MS (Chair), et al

    Read this Supplement to review the state of the art in treatments for insomnia, new research into understanding the sleep-wake cycle, and how that research might play out in treatments for insomnia.

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  • Misdiagnosis of Bipolar Depression in Primary Care Practices

    Larry Culpepper, MD, MPH

    Learn how to provide an accurate and timely diagnosis for your patients with bipolar disorder by differentiating unipolar and bipolar depression and assessing patients for manic and hypomanic episodes.

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  • Latest Guidelines and Advances for Treatment of Restless Legs Syndrome

    Christopher J. Earley, MBBCh, PhD, FRCPI

    Find out about treatment for RLS, including dopamine agonists, α-2δ agents, opioids, and iron, and discover how prescribing these agents on the basis of symptom frequency and pain level can help effectively manage RLS.

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Mechanism of Action of Antipsychotic Medications

Do you know how to match antipsychotic treatment to each individual patient’s illness presentation? Do pharmacokinetics and pharmacodynamics help? Update your understanding of the mechanism of action of antipsychotics and discover how you can tailor treatments to your patients with schizophrenia.




Journal CME


Demographic, Economic, and Clinical Correlates of Depression Treatment Response in an Underserved Primary Care Population

Dinesh Mittal, MD; Lakshminarayana Chekuri, MD, MPH; Liya Lu, MS; and John C. Fortney, PhD

Can you predict your patients' depression treatment response using demographic, clinical, and socioeconomic variables? Read this journal CME article to learn the results of a study of response to collaborative care for depression in federally qualified health centers.

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CME Partners

The Appropriate Use of Opiates in Chronic Pain

Autry J. Parker, MD, MPH

Review the use of opioid therapy for chronic pain and discover tools that can help you assess patients for abuse risk and safeguard them during treatment.

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