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  • Setting the Stage for Success or Failure: Making an Accurate Diagnosis of Bipolar Depression

    Henry A. Nasrallah, MD

    Patients with bipolar depression are too often misdiagnosed as having unipolar depression. Read this activity to learn clues to aid in making the correct diagnosis and how to detect signs of bipolarity in depressed patients.

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  • Recognizing and Assessing Risk Factors for Difficult-to-Treat Depression and Treatment-Resistant Depression

    Bradley Gaynes, MD, MPH

    What should you do when your patients don’t respond adequately to antidepressant therapy? Review this Case and Comment activity to find out about Alice's depressive episode and how you can help your patients like Alice achieve remission.

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  • The Effect of Comorbid Psychiatric and Medical Illnesses on Sleep Disorder Treatment

    Thomas Roth, PhD

    Learn about psychiatric, neurologic, and medical conditions that frequently coexist with sleep disorders and discover treatment strategies, both pharmacologic and nonpharmacologic, to improve patient outcomes.

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  • Neuroanatomy and Physiology of Cognition

    Larry Culpepper, MD, MPH

    New research on brain networks provides insight into cognitive deficits prevalent in patients with depression. Discover how disrupted connections and functions in various brain networks and regions contribute to cognitive symptoms and how new treatments are needed for these symptoms.

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Most Popular


Effective Treatment of Bipolar Depression: Monotherapy and Combination Strategies

To effectively manage bipolar disorder, you need to be familiar with evidence-based pharmacotherapy. Find out which pharmacologic strategies are the most effective for bipolar depression and which agents work well as monotherapy or adjunctive therapy.

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Journal CME


Benzodiazepine Use and Risk of Mortality Among Patients With Schizophrenia: A Retrospective Longitudinal Study

Cynthia A. Fontanella, PhD; John V. Campo, MD; Gary S. Phillips, MAS; Danielle L. Hiance-Steelesmith, MSW; Helen Anne Sweeney, MS; Kwok Tam, MS; Douglas Lehrer, MD; Robert Klein, PhD; and Mark Hurst, MD

Do you prescribe benzodiazepines to your patients with schizophrenia? Learn more about the risk-benefit profile of this strategy by reading this journal CME study. The findings on mortality risk may surprise you.

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CME Partners

Engaging Patients in Long-Term Management of Bipolar Disorder

Joanne DeSanto Iennaco, PhD, PMHNP-BC, APRN, and Julie A. Carbray, PhD, FPMHNP-BC, PMHCNS-BC, APRN

What strategies do you use to get patients with bipolar disorder to participate in their illness management? Play this game-based activity to see if you can help a long-term patient with bipolar disorder learn the importance of adhering to treatment, tracking mood states, and making important lifestyle changes.

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