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Featured Activity
Toward Depression Remission: Balancing Efficacy and Tolerability
Angel L. Montejo, MD, PhD

In this Brief Report, review presentations from the 21st Annual ECNP Congress, which focus on advances in MDD treatment in nonserotonergic brain pathways and how these pathways influence antidepressant profiles.

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Pain and the Brain: Lower Back Pain
Rakesh Jain, MD, MPH

Participate in this interactive case to assess Mr C’s tolerance for his current pain medication and learn what other factors should be evaluated to effectively treat his condition.

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Pharmacotherapy for Adult ADHD
Lenard A. Adler, MD

View this short summary to learn about pharmacologic and nonpharmacologic therapies for patients with ADHD and find out how to treat this illness in the presence of comorbidities.

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Featured Activity
Balancing the Equation: Managing Comorbidities in Patients With Severe Mental Illness
Roger S. McIntyre, MD, FRCPC (Chair), et al

NEW! Read this Supplement to find out how to prevent and manage medical illnesses in your patients with serious psychiatric disorders.

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Commentary: Defining and Managing Suicidal Risk in Patients Taking Psychotropic Medications
Jan A. Fawcett, MD (Chair), et al

NEW! In this Commentary, discover the dangers and benefits of medications used to treat mental illnesses and learn how to manage suicidal risk in your patients.

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Easing the Burden of Treatment-Resistant Depression
Maurizio Fava, MD (Chair), et al

Read this Academic Highlights to review treatment strategies for resistant depression and learn how to use measurement-based care to ensure complete recovery.

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Featured Activity
International Consensus Group on the Evidence-Based Pharmacologic Treatment of Bipolar I and II Depression
Siegfried Kasper, MD (Chair), et al

View this Academic Highlights to analyze the available evidence on the treatment of bipolar depression and evaluate how that evidence can be applied in your practice.

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A Roadmap to Key Pharmacologic Principles in Using Antipsychotics: Application in Clinical Practice
Sheldon H. Preskorn, MD

In this Academic Highlights, learn how the pharmacodynamic and pharmacokinetic properties of antipsychotic medications can help to individualize treatment and improve outcomes for patients.

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Proceedings and Data From The Schizophrenia Summit: A Critical Appraisal to Improve the Management of Schizophrenia
Henry A. Nasrallah, MD (Chair), et al

Read this Supplement to find out how the experts weighed in on 10 commonly held clinical beliefs about schizophrenia.

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multimedia curriculum
Diagnosing Bipolar Disorder in Children and Adolescents
Kiki D. Chang, MD

NEW! Here, review the diagnosis of bipolar disorder in younger patients and learn how to differentiate bipolar disorder from other childhood psychiatric illnesses.

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Depression Symptomatology and Neurobiology
Alan J. Gelenberg, MD

How do you distinguish between depression, sadness, and grief? What is the underlying neurobiology of depression? To find out, read this interactive activity.

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Managing Depression During Pregnancy
Marlene P. Freeman, MD

Participate in this short interactive summary to review benefits and risks to mother and baby of treatments for your depressed pregnant patients.

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Switching Treatments for Complicated Depression
Maurizio Fava, MD

View this activity to learn about switching strategies to help your patients with resistant depression who have achieved no response or only partial response to treatment.

Diagnosis and Treatment in Bipolar Depression
Charles L. Bowden, MD

Your patients with bipolar depression may not be receiving adequate care. In this interactive patient case, discover the best methods for correctly diagnosing and treating bipolar depression.

Online Poll

Please take a moment to answer 2 questions about schizophrenia.

1. You diagnose Mr Y, a 30-year-old single man, with schizophrenia. Before initiating treatment with an antipsychotic, you counsel Mr Y about the risks of weight gain. Which of the following best describes the baseline information you will gather concerning weight?

Body mass index (BMI) and fasting plasma glucose level

BMI and waist circumference

BMI, weight, and lipid profile

BMI, weight, waist circumference, lipid profile, and fasting plasma glucose level

2. Mr Y’s baseline BMI was 29.0. You are concerned about potential weight gain, so you select a weight-neutral antipsychotic. At 4 weeks, Mr Y has responded well to treatment, and his BMI did not change. What is your next step?

Continue current treatment and add pharmacotherapy for weight loss

Add behavioral weight loss strategies (eg, diet and exercise)

Switch to another antipsychotic to promote weight loss

Consider bariatric surgery

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